Emma is a businesswoman coming from Australia to the U.S to sign a controversial oil contract. On her way to a press conference, she jumps into a taxi. Soon after, to her surprise, she is attacked and drugged by the taxi driver. She wakes up tied to a chair in a filthy cabin. Emma soon learns she's the night's amusement for a man named Jim and his loyal associates Pete and Shir...
画皮师是随天地而生的古老职业，历代画皮师仅凭一只神奇的画笔行走世间，可为人重塑筋骨，易容改貌。 这一代的画皮师方祭本该在几十年前死去，却因他师父以命相救而活了下来，在经历了“不老”的数十年后，方祭仿佛是被“画皮师”三字禁锢了的人，他试图挣脱“画皮师”的枷锁，却最终无法割舍自己背负的责任。画皮师自古以来都遵循着古训，一师一徒秘传着画皮的法术。方祭的徒弟穆一骞乐观、直率且阳光是机关术方面的天才。他曾是京城内有名的富家少爷，在遇到画皮师后穆一骞抛弃了过去的浮华生活，跟着方祭云游四方。
周晴和陈北在刘旭婚礼中相识，周晴因意外失去味觉，陈北一路照顾她，两人渐渐互生情愫并相爱，但两人性格迥异，在各自追求梦想的路上渐行渐远，几年后在初次见面的派对再见时已是物是人非。
